162–325 mg (non-enteric coated), chewed and swallowed.
Continue with 81 mg daily indefinitely.
Hypersensitivity and major GI intolerance.
Clopidogrel.
Relief of anginal symptoms, uncontrolled hypertension, and acute heart failure.
5 mg sublingually, repeated every 5-10 minutes as needed (maximum of 3 doses).
For persistent angina despite sublingual NTG.
40% via facemask if saturation is < 94% or if in distress.
IV morphine.
5 mg diluted with 10 mL of water or sodium chloride, slow IV.
Within the first 24 hours of presentation.
25 mg orally twice daily as tolerated.
Nondihydropyridine CCBs (diltiazem, verapamil).
120–360 mg/day orally.
Primary PCI.
Improves survival, establishes consistent revascularization, reduces risk of stroke and re-infarction.
IV 1.5 million units diluted in 100 mL sodium chloride, infused over 30–60 minutes.
Previous allergy, CVA within last 3 months, active bleeding, recent major trauma, and others listed.
Alteplase, IV infusion.
IV, 30 mg as a bolus, followed by SC, 1 mg/kg as a single dose.
5 mcg/minute, titrated to response.
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Discover key recommendations for acute supportive care in Acute Coronary Syndrome (ACS), including aspirin, nitrates, oxygen, and morphine management to enhance patient outcomes and ensure effective treatment strategies.
1. What is the initial dose of aspirin recommended for all ACS patients without contraindications?
2. For how long should aspirin 81 mg be continued after the initial dose in ACS patients?
3. What is the recommended treatment for ACS patients with hypersensitivity to aspirin?
4. What is the initial dose of intravenous nitroglycerin (IV NTG) for persistent angina despite sublingual NTG?
5. When should oxygen therapy be administered to ACS patients?
Acute Coronary Syndrome (ACS) requires timely and effective management strategies to prevent complications and improve patient outcomes. This overview consolidates essential treatments, including medications and their administration guidelines.
Primary PCI
Fibrinolysis
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